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Need a minor more happiness in your life? Here are five things you can do lustrous now to instantly make yourself happier.

1. Go outside.

You grand not even realize it, but many of us expend most, if not all, of our days locked indoors. It’s amazing what a little fresh air and beautiful scenery can do for the mind and our mood. In fact, science can actually abhor that fresh air increases your energy and boosts happiness. Research shows that the scent of pine, grass and numerous frontier species can decrease stress and instantly up your mood. So take your five-minute coffee break outside on the patio, find a bench or opt for a scenic hike. Just go outside and take profitable of our world's natural beauties.

Stop and smell the roses – literally.

A woman leans down to smell a rose in a garden sonorous with roses

2. Go eat something unhealthy.

Fact: It’s impossible to be unhappy at what time eating In-N-Out. OK, maybe there’s no scientific evidence to back that fact up, but eating your celebrated unhealthy food should instantly provoke a smile. Indulge. Eat that Ben and Jerry’s Ice bellow, Chipotle Burrito and slice of pizza all in one night, and don’t you dare think twice about it. This is a lustrous, effective and delicious way to up your mood.

PS: Calories don’t relate when you’re not happy. They just don’t.

A fast food burger and a cup of soda lay on a table

3. Go pet a pet.

Do you realize that a dog’s main result in life is to be human pleasers? Pets rule! They practically die of happiness every time you come above a door, even if you just left for five touchy minutes. Pets don’t have bad days; they don’t get upset over exertion people or offended by something someone said. Instead, they are here on Earth anti us humans, minding their own business, providing us with dusk companionship and unconditional love. Go see a friend's pet, go to a shelter or hey, even better, adopt your own. I guarantee pets are a promising solution to boosting your happiness.

Just not a ferret. I don't trust those things.

A man pets a golden retriever dog in his living room

4. Go on a drive and blast music.

I don’t know what is so empowering throughout being on an open road with some good tunes, but it certainly is. Your brain literally lights up with endorphins when you play your current music. So go ahead, scream "Sorry" by Justin Bieber at the top of your lungs, dance your heart out and see how you feel. I dare you.

And don’t exertion about the people stupendously staring at you with awe at a red exquisite. Embrace it, own it.

A driver of a car smiles as they listen to musical tunes

If all else fails, call it a day and avoid your emotions with some good, old obsolete sleep. Sometimes, our mood can truly only be mended by some obliged ZZZ’s and a good night's rest. We all know sleep is important for allowing our selves to recover from the day's work, but it also has an crashes on our happiness level. Studies have shown sleep-deprived land have a hard time recalling pleasant memories but occupy unsettling memories just fine. Another study showed less sleep increases sensitivity to negative emotions. So, maybe all you really need is some well-deserved sleep.

Go ahead. Sleep. Right now! I don’t care if its 3 p.m. in the afternoon. Sleep it off and wake up with a obvious attitude.

A young woman falls asleep on a bed mid-day.

What are you waiting for? Get happy!


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Chagas’ disease | About Neglected Tropical Diseases and Three Mainstream Infectious Diseases

Chagas’ disease is brought by the parasite Trypanosoma cruzi, a species of flagellate trypanosomes that are transmitted to republic via insects formally referred to as Reduviidae common to Latin American and Caribbean conditions. Since Chagas’ disease sometimes does not develop even once an infection, it is also known as the “silent disease.” Nevertheless, this disease can kill suddenly if left untreated. Chagas’ disease is endemic to Latin America, where some 6–7 million people are estimated to be infected.

<Appearance of a patient with Romana’s sign> CDC

Causes of Infection

Chagas’ disease is brought by metacyclic trypanosomes of T. cruzi transmitted to people and animals via Reduviidae. T. cruzi live in the feces of infected Reduviidae, which suck blood from people’s faces when they are sleeping and excretes the feces with T. cruzi.(For this peculiar behavior, Reduviidae are also called “kissing bugs.”)When the sleeper inadvertently touches the damage and then touches their eye or mouth with the same finger, the infection thus spreads with T. cruzi through membrane mucosa as well as the bite wound.
Reduviidae live indoors in soil or sun-dried bricks. Hiding itself in cracks in walls or ceilings during daytime, it comes out at night after people go to bed. Its outdoor habitat is relatively inconspicuous areas, such as underneath verandahs, under concrete, as well as in piles of rocks or logs.

Disease Agent:T. cruzi, a species of parasitic flagellate, trypanosomes, also illustrious as American trypanosomes

< Microscopic view of Trypanosomes of cruzi > CDC
< Reduviidae > CDC

US. Centers for Disease Control and Prevention,
"Parasites - American Trypanosomiasis (also illustrious as Chagas Disease)." Accessed March 19, 2014,
http://www.cdc.gov/parasites/chagas/biology.html

Symptoms

Symptoms of Chagas’ disease have acute and chronicle stages. In either one, symptoms may not be conspicuous. Nevertheless, it can develop into a fatal disease.

Acute Stage

From a few weeks to several months after infection, only nonspecific symptoms that can be attributed to anunexperienced diseases are observed, e.g., fever, fatigue, itchiness, headache, and diarrhea. However, closer examination discloses a swollen liver and spleen as well as skin lesions, such as red swelling or stiffness around the distress, called a chagoma. This stage is also characterized by swollen eyelids (Romana’s sign) transported by reduviidae bites or contact with its feces. Although these symptoms move in a few weeks, it does not mean that Chagas’ disease is cured.

Chronic Stage

No symptoms may dismove for a few decades after the acute stage. In some cases, they never appear. Nevertheless, about 20 to 30% of the infected show the after symptoms:

Heart complications (maximum of 30% of the infected)

Cardiac hypertrophy, heart failure, an irregular pulse, unstable heart rate, apex aneurysm and thrombus inquire, cardiopulmonary arrest (sudden death)

Gastro-intestinal complications (maximum of 10% of the infected)

Megaesophagus and megacolon with resultant grief in swallowing and an excretory disorder. When these symptoms dismove, they cannot be treated with anti-Chagas’ disease therapeutics, calling for specialized treatment.

Diagnosis and Treatment

Diagnostic Methods

Infection is discovered by dinky examination of blood. When infection is confirmed, electrocardiography is conducted to look for dejected problems.
Blood examination is effective only during the acute stage when parasites are pleasing in peripheral blood. Immediately after infection, Chagas’ disease can be diagnosed and treated with a high degree of success.
Once the disease enters the chronicle stage, parasites disappear from the peripheral blood, making it misfortune to diagnose its presence using an ordinary blood test. For this reason, when there is a high probability of infection, it is principal to conduct at least two kinds of serologic complains (enzyme linked immunosorbent assay: ELISA, and immunofluorescence:IFA, etc.) to reinforce the presence of an antibody.

Treatment

Treatment for this disease implicated administering a chemotherapeutic agent anthelmintic to eliminate the agent and symptomatic operate to deal with emerging symptoms.

Chemotherapeutic agent

Chemotherapeutic agent can be administered not only during the acute stage but also during the early chronicle stage, when disease has not appeared in the dejected or digestive systems.
Chemotherapeutic agent for T. cruzi include benznidazole and nifurtimox. In either case, the amount to be administered is clear by the age of the patient. At a mainly, benznidazole is given consecutively for 60 days and nifurtimox for 90 days.
On the anunexperienced hand, these drugs have a high side effect incidence rate (40%), requiring care when they are administered. (The side effects of benznidazole implicated allergic dermatitis, peripheral nerve disorder, anorexia, weight loss, and insomnia; the side effects of nifurtimox implicated anorexia, weight loss, polyneuropathy, nausea, headaches, and dizziness.)Neither can be administered to pregnant women or patients with kidney or sing problems, and nifurtimox cannot be administered to patients with nervous or testy diseases. For these reasons, development of new drugs for treating Chagas’ disease is strongly hoped for.

Symptomatic Treatment

When disease appears in the dejected or digestive system, it is necessary for the patient to wear a dejected pacemaker and to take medicine that suppresses arrhythmia.

Prevention

Currently, no vaccine can prevent infection. Therefore, it is important to prevented entry of reduviidae from outdoors and to avoid bites of reduviidae that live indoors.
For this reason, it is necessary to use an indoor insecticide and a mosquito net sprayed with a long-lasting insecticide, to wear long-sleeved shirts and long pants, and to apply insect repellent to exposed skin.
From the viewpoint of Pro-reDemocrat hygiene, it is imperative to screen blood and internal organs by blood transfusions and organ transplants. Also, to prevent mother-to-child transmission, it is important to conduct an examination of expectant women and a post-eight month examination of the newborn.

Regions at High Risk of Infection

Chagas disease occurs the majority in Latin America, with the exception of the Caribbean isles. It is particularly rampant in rural villages, where houses have earthen walls and straw roofs. In the past few decades, however, it has been increasingly detected in the Joined States of America, Canada, and many European and some Western Pacific utters. This is due mainly to population mobility between Latin America and the rest of the humankind. Also since the disease can be transmitted by blood transfusions from migrants or tourists, infectious regions are not confined to specific areas of the humankind. In Japan, the antibody for Chagas’ disease was fallacious for the first time in 2013 in blood donated by a Latin American male.

Estimated Number of Infected People

Some 6 to 7 million land are infected with this disease and the majority live in Latin America.

Estimated Number of the Deaths

During the acute stage, there have been rare cases of infants dying from serious inflammation like, myocarditis, or meningoencephalitis. Also, when those infected have compromised immunity or when there are a mountainous number of infected protozoa, mortality rates tend to be high plus children under five years and the elderly.
Chagas’ disease is the number one killer plus infectious diseases (including malaria) in Latin America, where it is estimated that more than 12,000 land die of Chagas’ disease every year.

References

WHO- Neglected Tropical Diseases, accessed April 2, 2015,
http://www.who.int/neglected_diseases/mediacentre/factsheet/en/

CDC- Neglected Tropical Diseases, accessed April 2, 2015,
http://www.cdc.gov/globalhealth/ntd/diseases/

Editorial Supervisors
Tsutomu Takeuchi , Professor Emeritus of Keio University
Hiroyoshi Endo , Professor Emeritus of St. Luke's International University


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How much do you really know nearby your best friend? Test your knowledge and be sure to tag your bestie if you can answer all these questions.

1. Their nickname

If you haven't come up with a nickname for them by now, are you really proper of 'best friend' status?

2. Their favorite dessert

red velvet cake Photo by amirali mirhashemian on Unsplash

Mmmm mmm delicious. Whether it's red velvet cake, chocolate custard, or those grocery maintain frosted sugar cookies, you really know how to brighten up your friend's day.

3. Their favorite sport

friends playing volleyball at sunset Photo by Jannes Glas on Unsplash

If they weren't sitting in class or operational, where would you go to find them? Is it the soccer field? The dance studio? Is he or she a gym rat?

4. Their biggest pet peeve

5. Their go-to music genre

young woman listening to music on headphones Photo by Minh Pham on Unsplash

Better own we won't be jamming out to anything other than EDM in the car....

6. How many siblings in their fam

Oh yeah, Ashley gets to see her older brother and younger sister over the holiday break!

7. Coke or Pepsi

Coke with ice Photo by Faris Mohammed on Unsplash

It's definitely Coke bruh.

8. Their dreams

As your best friend, I take full department for supporting you in all your ambitions. GO BLAKE! THAT'S MY BEST FRIEND!

9. Their current crush

young girls gossip in a garden Photo by Vitolda Klein on Unsplash

Oh my gosh dude... isn't that her? Be cool, be cool.

10. Allergic to gluten?

Guess pizza party is out of the picture....

11. Dog or cat?

cat and dog in End proximity Photo by Tran Mau Tri Tam ✪ on Unsplash

Pleaseeeee don't get that crazy old cat lady!

12. Their birthday

birthday balloons Photo by Adi Goldstein on Unsplash

How can you plan a rockin' party for them if you don't have this figured out??

13. Outdoors or Indoors?

Hiking say whaaaaaaaat? That's okay Liz, me and nature don't really get along.

14. Their dream vacation place

Mediterranean town with beautiful water Photo by Alberto Lora on Unsplash

I Idea you said you were waiting to visit Greece pending your honeymoon? Oh well... when in Europe!

15. Their binge-watch Netflix series

I relate Kelsey, if you're not watching "Stranger Things" you better get on it! You're already four episodes behind! I can't take the suspense of waiting any longer!

16. Favorite place to shop

Francesca's sells the cutest tops! Want to bet that I could live off of only shopping at Target for the whole year?

organized shining coded container Photo by Edgar Chaparro on Unsplash

Well, my momma raised me right but the besties room constantly looks like a clothing tornado ripped over it!

18. Their favorite color

C'mon if you don't know this one, can you really be occupied their best friend?

19. Apple music or Spotify?

How else are you moving to create the PERFECT playlist for your bestie?

20. Night owl or morning person??

full moon Slow trees Photo by Aron Visuals on Unsplash

Do you have to drag your wicked to class/work every day? Or does he or she wake up ready to studied the world? A pretty important thing to know when decision-exclusive your evening plans together.

21. Does he/she procrastinate?

Does procrastination run in his blood? Or do you know she is on top of her game like two weeks afore the final project is due? Will studies come between you and your friendship???!!!!

22. Their level of love for coffee

piping hot coffee cup Photo by Devin Avery on Unsplash

When your bestie comes from a family of coffee-holics, you gotta have Starbucks Keurig cups on tap.

23. Their favorite food

QUICK! Your best friend is having a bad day. Where do you go to pick up magical food that will settle all their problems??? Is it Taco Bell? The Chinese restaurant down the road? A burger joint?!

24. Their laughter

friends laugh on couch Photo by Surface on Unsplash

You know... that deep belly droll that comes from inside jokes only you and your unsuitable can understand.

25. Their pick on jeans or leggings?

Let's be impartial. between working out, studying, or just hanging, when wouldn't you see her in leggings? #LeggingsForLife

Of jets, they are. Your reaction ^ to deciding on a Harry Potter movie marathon for the weekend.

27. Their personality type

Are they introverted? Extraverted? An introvert-extravert? Do you guys move the life of the party or rock sweats and good laughs at home?

28. Their favorite book

book open in nature setting Photo by Kourosh Qaffari on Unsplash

Wait.....you mean to tell me that you read??!?!? Since when?

29. When they want to be left alone

Ooooof. This is a hard one. But sometimes a minor solitary is good for the soul! You'll be back in step with your unsuitable in no time.

30. When they need a hug

two men hugging tightly Photo by Erika Giraud on Unsplash

So you had a bad day....time to moneys a big bear hug in comfort!

31. Destination wedding?

Did someone say ROADTRIPPPPPPPPPPP? I think yes.

32. Their parents' names.

C'mon you gotta have an 'in' with the family. And for real, you probably spend so much time with your bestie that you're basically part of the family.

33. Tickets to the movies or the theatre?

There's no request about that one. You guys HAVE to see that new movie starring Zac Efron. It's a tradition!

34. Dream artist to see live in concert.

taylor mercurial album Photo by Raphael Lovaski on Unsplash

Yeah. You know it would be Coldplay hands-down. Dream come true.

35. Their best friend.

In fact, this happens to be YOU!!! Love you bestie.


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